Saturday 29 September 2018

CBD May Help Treat Methamphetamine Dependency, States New Study

Cannabidiol (CBD) can “reduce the motivation to seek and consume methamphetamine”, suggesting it may be effective as a treatment for those addicted to the drug, finds a new study published by the Journal of Psychopharmacology.

“Methamphetamine is an addictive stimulant that can cause many adverse physical, psychological and psychosocial effects”, begins the study’s abstract. “Preliminary evidence shows cannabidiol, a non-intoxicating constituent of the cannabis plant, may have efficacy in treating opioid and nicotine dependence. However, no study has yet examined whether cannabidiol treatment might impact on methamphetamine addiction.”

The current study “investigated whether cannabidiol administration reduces the motivation to self-administer methamphetamine and relapse to methamphetamine-seeking behavior following abstinence.”

Thirty-two male Sprague Dawley rats with implanted jugular vein catheters were initially trained to self-administer methamphetamine via lever press during two-hour sessions on a fixed ratio 1 schedule of reinforcement. Rats in experiment 1 ( n=16) then advanced to a progressive ratio reinforcement schedule to examine the effects of cannabidiol (0, 20, 40, and 80 mg/kg intraperitoneal) on motivation to self-administer methamphetamine. Rats in experiment 2 ( n=16) were tested for cannabidiol effects on methamphetamine-primed reinstatement following extinction.

“Cannabidiol (80 mg/kg, but not 40 mg/kg, or 20 mg/kg) reduced the motivation to self-administer methamphetamine and attenuated methamphetamine-primed relapse to methamphetamine-seeking behavior after extinction”, states the study.

According to researchers,. this is the first demonstration “that cannabidiol can reduce the motivation to seek and consume methamphetamine, and suggests that cannabidiol might be worth trialing as a novel pharmacotherapy for methamphetamine dependence.”

The full study, conducted by researchers at Macquarie University and the University of Syndey, can be found by clicking here.

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Here is the Most Expensive Bong in the World

The most expensive bong in the world (pictured below) is available now for just $1 million!

The website selling The Throne states that it’s considered to be “one of the most iconic and legendary functional glass pieces in the industry”. Standing nearly two feet tall, the piece was constructed in 2010. The skulls were made by Scott Deppe, and remove from the top to reveal the mouthpiece. The structure was assembled by Darby Holm using the Deppe’s Darkness color.” Banjo, the third collaborator, “constructed the one foot tall goddess that sits upon Darby’s lattice of bones.”

The airflow of this piece “begins at the push bowl, where it travels down into a large natural percolator and then on up the skeletal backbone to the mouthpiece.” Since this piece was first exhibited, “there have been several similar pieces created, but this one will always be considered the true original.”

The Throne can be viewed at Illuzion Glass Galleries in Denver, Colorado, and can be purchased online by clicking here.

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Here is the Most Expensive Bong in the World was initially published on Nick Adams' Blog



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Friday 28 September 2018

Study: Cannabis Oil Reduces Seizures, Improves Quality of Life, in Those with Dravet Syndrome

According to a new study, cannabis oil (containing both CBD and THC) is effective in reducing seizure counts and improving quality of life measures in those with Dravet Syndrome.

An epilepsy word cloud.

The study, titled A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome, was published by the journal Annals of Clinical and Translational Neurology.  According to the Dravet Foundation, dravet syndrome, also known as Severe Myoclonic Epilepsy of Infancy (SMEI), “is a rare and catastrophic form of intractable epilepsy that begins in infancy”, with “an estimated incidence rate of 1:16,000 to 1:21,000”.

The study’s abstract starts by stating that “Both Δ9 Tetrahydrocannabidiol (THC) and cannabidiol (CBD) components of cannabis, have been shown to have anticonvulsant effects. Cannabis oils are used to treat seizures in drug-resistant epilepsy (DRE).” It then goes on to note that “Recent trials provide data on dosing, side effects, and efficacy of CBD, yet there is a paucity of information on THC in epilepsy.”

The primary objective of the study “was to establish dosing and tolerability of TIL-TC150 – a cannabis plant extract produced by Tilray®, containing 100 mg/mL CBD and 2 mg/mL THC- in children with Dravet syndrome. Secondary objectives were to assess impact of therapy on seizures, electroencephalogram (EEG) and quality of life.”

For the study, twenty children “received add-on therapy with TIL-TC150. The dose ranged from 2 to 16 mg/kg/day of CBD and 0.04 to 0.32 mg/kg/day of THC. Patients were monitored for tolerability and adverse events, and secondary objectives.”

Nineteen participants completed the 20-week intervention. Mean dose achieved was 13.3 mg/kg/day of CBD (range 7-16 mg/kg/day) and 0.27 mg/kg/day of THC (range 0.14-0.32 mg/kg/day).

“There was a statistically significant improvement in quality of life, reduction in EEG spike activity, and median motor seizure reduction of 70.6%, with 50% responder rate of 63%”, states the study.

Researchers  conclude; “TIL-TC150 was safe and well tolerated in our subjects. TIL-TC150 treatment resulted in a reduction in seizure counts, spike index on EEG, and improved quality of life measures. This study provides safety and dosing information for THC-containing cannabinoidpreparations.”

For more information on this study, click here.

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Medical Cannabis for Pets Bill Signed Into Law by California Governor

California Governor Jerry Brown has signed into law legislation that explicitly allows and regulates the medical use of cannabis for pets.

Assembly Bill 2215 was given approval by the full Senate in August by a vote of 37 to 1 vote, roughly three months after the Assembly passed it 60 to 10.  Governor Brown signed the measure into law yesterday.

Assembly Bill 2215 would expand “the intent of the Medicinal and Adult-Use Cannabis Regulation and Safety Act (MAUCRSA) to control and regulate cannabis and cannabis products for medicinal use on pets.” It would define “cannabis products” to include products intended for medicinal use on a pet, and although it wouldn’t allow a veterinarian to administer medical cannabis, it  would “allow a veterinarian to discuss the use of cannabis on an animal for medicinal purposes without being disciplined or denied, revoked or suspended by the Veterinary Medical Board (VMB).”

The measure states that the VMB “would have until July 1, 2019 to promulgate guidelines for veterinarians to follow when discussing the use of cannabis”, and it “Provides that a cannabis product for use on a pet may only be sold to an adult 21 years or age or over by a licensee who has been issued a retailer license, as specified.”

The full text of Assembly Bill 2215 can be found by clicking here.

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The Top 15 Fun Things To Do While High | HonestMarijuana

Woman smoking weed & thinking about things to do while high

Being high is pretty damn great all by itself. But sometimes just sitting there stewing in your own psychedelic juices isn’t enough. You need something more. That’s when you start looking for fun things to do while high.

And while recreating the stunts from Jackass, making a backyard wrestling video, or taunting a badger is never a good idea, there are plenty of less dangerous activities that make being high even better than it already is.

Top 15 Fun Things To Do While High

1) Dance

Yes, gravity (and couch lock) can be rough, but you’ll enjoy your high more if you get up and move once in a while. Pick a type of music that gets your foot tapping, crank up the volume, and let your body move to the beat.

2) Tai Chi

Capitalize on your heightened awareness by learning and performing some Tai Chi. You’ll be more aware of your breathing, your heartbeat, and the flow of energy from head to toe and back again. That’ll make Tai Chi, and being high, more stimulating.

3) Hula Hoop

Hula-hooping as one of the things to do while high

We never could hula hoop sober. But after a few tokes on an Honest Blunt, we could damn near turn pro (if that were a thing…which it should be). There’s something extremely satisfying about finding the rhythm in your hips that keeps that hoop spinning.

Add in a bit of your favorite music, and the experience will be transcendent.

4) Go To The Circus

Sure, you probably got your fill of the circus when you were a kid, and now it’s nothing special. But the circus can be seriously mind-blowing again if you hit your bong first.

Don’t have a circus near you? Really, anything with a lot of movement and flashy colors will work (e.g., Cirque du Soleil, Stomp). And if you really have no other options, stick in The Greatest Showman and get your fix that way.

5) Tour An Art Museum

This one is simple: get blazed, go to an art museum, enjoy. The buzz amplifies the aesthetics and puts you in a whole ‘nother headspace. Put some headphones in your ears and some Jolly Ranchers candy in your mouth, and three of your five senses will trip the light fantastic.

6) Study Or Read A Book

It may not sound like a terribly good time, but studying or reading a book can be incredible after partaking of the wacky weed. The things you’ll learn will literally expand your consciousness.

7) Surf The Web

There’s so much to see, hear, and do on the internet that you can’t possibly experience it all in one lifetime. That makes it a great source of fun when you’re high. You can discover new things, laugh, cry, and chill all with just a few clicks or taps.

8) Yoga

Yoga is basically stretching, so you’ll do your body good and feel better all at the same time. Plus, there’s no real commitment like there is with trying to finish a book or find your way to the circus. WHERE IS THIS EFFING PLACE?

9) Clean

Cleaning is wholly un-enjoyable when you’re sober. But throw in a bit of canna-goodness and you’ve got a sensational, Zen-like experience that can’t be beat.

They don’t say that cleanliness is next to godliness for no reason. Get your divinity on and clean your space. You’ll be happy that you did.

10) Go To A Playground And Swing

Man swinging while high

Remember how amazing it felt to swing when you were a kid? Now you can experience that feeling again. Burn a doobie, head to a nearby playground, hop on a swing, and pump your legs as hard as you can.

Don’t worry, you won’t be able to turn a full circle no matter how hard you try.

11) Have Sex

Which one is better: being high or having sex? Honestly, it’s pretty much a dead heat. But what about having sex while high? Yep, they both make the other so much better.

To add to the experience, try a bit of cannabis lube to see just how amazing sex and cannabis can be.

12) Take A Walk

The sights. The sounds. The fresh air. It’s all made better with a bit of Mary Jane in your system. Your neighborhood will never look the same again.

13) Do A Little Cardio

Jogger thinking of things to do while high

Exercise releases endorphins. Endorphins make you feel good. Nuff said.

If you opt for the cardio route as your fun thing to do while high, choose an exercise that’s relatively simple and familiar to you. Dancing the Viennese Waltz or biking in traffic should probably be left for another time.

14) Hang With Friends

Hanging with friends inevitably leads to some seriously deep conversations (“I heard about this guy who invented a car that runs on water, man. It’s got a fiberglass, air-cooled engine, and it runs on water!”).

15) Meditate

Woman meditating while high

Meditating when you’re sober can be a difficult and boring pastime. But when you’re high on the chronic, it can be a fun and exciting activity. Just puff some pot, relax, and let your thoughts drift through your awareness like you were watching a movie. Ahhh, bliss.

Honorable Mention

These didn’t make the top 15, but they’re still some pretty awesome things to do while high.

 16) Make Lists

We like to make lists while we’re high. How do you think this list came about?

17) Play Video Games

You haven’t lived until you’ve played Paperboy while trippin’ balls.

18) Watch A Movie

We love watching movies without marijuana, so it doesn’t take much to convince us to drop in a DVD (or better yet, a Blue-ray) when we’re bombed on Blue Dream.

19) Play Weed Games

Wanna have fun and keep your high rolling? Play a weed game. We’ve assembled a list of the 21 best weed games ever so you don’t have to think too much.

In fact, some of the activities on this list — like watching a movie and listening to music — can be gamified so you can kill two birds with one stone.

(Metaphorically speaking, of course. Killing birds is not okay. Don’t do it.)

20) Type On An Old-School Keyboard

Old keyboard

Remember those clicky keyboards from the 1980s and 90s? They can be a really fun thing to do while high. If you can touch type, close your eyes, focus on the feel and sound of the keyboard, and just record your thoughts as they come to you.

21) Make Some Art

Wanna let your creativity run rampant? Make some art while you’re high. All you need is a pencil and paper. If you have some crayons, colored pencils, or paints, break ‘em out and let your inner 10-year-old shine.

22) Try New Food

You’re going to be hungry anyway, so why not use it as an opportunity to try new foods? Who knows? You might find your new favorite.

23) Take A Shower

When you’re out of your mind on Cherry OG, your nerve endings will be buzzing and your senses will be super sharp. Take advantage of this new-found awareness to take a hot shower. You can thank us later.

24) Get A Massage

Someone getting a massage as one of the things to do while high

Now that you’re all clean, continue the stimulation (oooh, sounds dirty) by giving and getting a massage. Of course, that only works if someone else is there with you. And who knows, maybe number 24 will lead to number 11 (as all things really should).

25) Give/Get A Temporary Tattoo

We’ve never done this one personally, but plenty of other people swear by it. Drawing on each other with washable pens — please make sure they’re washable — can be a tickly good time.

Plus, it’s a fun and simple form of foreplay if you’re into that sort of thing (who isn’t, right?).

Create Your Own List Of Fun Things To Do While High

Take a cue from number 16 on this list and make your own list of fun things to do while high. In fact, making a list of fun things to do while high while high sounds like an amazingly good time. Once you’ve got your list on paper, start checking them off.

If you find that something on your list is better in theory than in reality, don’t be afraid to erase it. We used to have skateboarding on our list, but since we don’t really know how to skateboard (and aren’t the most coordinated group) the whole thing devolved into a lot of falling (and an impromptu trip to the emergency room).

It’s not on our list anymore.

Whatever you do, don’t be afraid to try new stuff. That’s one of the wonderful things about weed: it opens you up to new experiences. Something you never in a million years thought you’d enjoy suddenly becomes the most fun you’ve had in your life.

For more information on all things cannabis and to check out our 100-percent all-natural marijuana products, visit HonestMarijuana.com today

The post The Top 15 Fun Things To Do While High | HonestMarijuana appeared first on Honest Marijuana.

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Thursday 27 September 2018

Chart: The History of U.S. State Marijuana Ballot Initiatives


On the 2018 Ballot

Mormons Oppose Marijuana Initiative in Utah Despite History of Cannabis Use

Michigan Is Poised to Become the 10th State to Legalize It

Dueling Initiatives in Missouri Likely to Confuse Voters

Recreational Legalization on the North Dakota Ballot

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Ask candidates for the Maryland Legislature to commit to supporting marijuana policy reform

The latest Goucher poll shows that 62% of Marylanders “support the legalization of marijuana for recreational use.” Unfortunately, Maryland’s lawmakers have lagged behind the public on this issue — but this could change in November’s election. If you are a Maryland voter,  please let the candidates in your district know that this issue is important to you. (And don’t forget to check out the Maryland Cannabis Policy Coalition’s Voter Guide here.)

If you are interested in hearing more about MPP’s work — and meeting our new executive director, Steven Hawkins — please consider attending the Spark! Maryland networking event on October 4 at 6:30 p.m. at The Reserve at Two Rivers, 4105 Mountain Road, Pasadena, MD 21122. You can purchase tickets here.

Marylanders are ready to join the eight other states that have legalized and regulated marijuana for adults 21 and older. Click here to ask the people who want to represent you in the General Assembly if they’re ready too.

The post Ask candidates for the Maryland Legislature to commit to supporting marijuana policy reform appeared first on MPP Blog.

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Rick Steves to tour Michigan in support of legalization ballot measure

Next week, legendary travel host Rick Steves will be visiting Michigan to give talks in support of Prop 1, the ballot initiative to legalize and regulate marijuana. Known for his hit PBS series “Rick Steves’ Europe,” Rick’s engaging personality and first-hand experience seeing the benefits of legalization in his home state of Washington make this an event you don’t want to miss.

You can catch him in two locations, Grand Rapids and Ann Arbor. Both speaking events are free and open to the public. The tour schedule is listed below.

TUESDAY, OCTOBER 2
It’s Time for a New Approach: Rick Steves on why legalization is a better solution
Time: 7:30 p.m., doors at 7:00 p.m.
Location: Peter Martin Wege Theatre, 341 Ellsworth Ave. SW, Grand Rapids
Cost: FREE
Register here

WEDNESDAY, OCTOBER 3
It’s Time for a New Approach: Rick Steves on why legalization is a better solution
Time: 8:30 p.m., doors at 8:00 p.m.
Location: Rackham Amphitheatre, 915 E Washington St., Ann Arbor
Cost: FREE
Register here

As a board member of NORML, Rick Steves has been a long-time advocate for sensible marijuana policies. Audiences around the country have heard his informative and entertaining talks on marijuana legalization, and now you have a chance to see him, too. Register for one of the events above and share the word by inviting friends and family.

The post Rick Steves to tour Michigan in support of legalization ballot measure appeared first on MPP Blog.

from https://blog.mpp.org/tax-and-regulate/rick-steves-to-tour-michigan-in-support-of-legalization-ballot-measure/

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Wednesday 26 September 2018

How Long Does Weed High Last: The Definitive Answer

Clocks telling how long does weed high last

If there’s one question that everyone seems to wonder about — but no one knows the answer to — it’s, “How long does weed high last?” If you’re new to the world of marijuana, don’t feel bad asking this question. Even many long-time cannaseurs have a hard time giving a conclusive answer.

But not us! We know what you want to hear. So in this article, the cannabis experts at Honest Marijuana give you the definitive answer to the question how long does weed high last.

How Long Does Weed High Last?

The best way to answer that question is by saying, “It depends…” We know that’s not very definitive, but let us finish. Before you get angry and storm off, the duration of your weed high really does depend on the way you consume your THC.

What that means is that you can tailor your experience by choosing from among the many different methods of getting THC into our body. Once you decide that, we can give you a much more definitive answer to your question.

Here’s how the durations break down based on method of consumption.

Smoking

Smoking is one of the most common ways to get your ganja on. The tools used for smoking are literally legion and include:

Basically, any time you inhale the smoke or vapor from a marijuana product, you’re smoking.

How long does a smoking weed high last? 1-3 hours

Edibles

Woman who's high on weed

There are so many ways to make your marijuana into edibles that you’re really only limited by your creativity. Our favorite edibles include:

Yes, that’s right. Milk, tea, and pills are included on this list. Basically, anything that you put in your mouth and swallow can be considered an edible.

How long does an edibles weed high last? 4-6 hours

Some stoners have even reported tripping for as long as 12 hours off a high-quality edible, but those claims are largely apocryphal.

Topical Application

Topical application of hemp

Topical application (on your skin) is becoming a very popular method of consumption among those looking for medical benefits from their cannabis. There are even multiple means of applying topical marijuana to your skin. They include:

The key thing to remember about topical applications is that they won’t cause a weed high. This is because your skin absorbs the cannabinoids very slowly.

So by the time the THC reaches your bloodstream after traveling through the layers of your skin, its potency has been reduced significantly (enough not to cause any psychedelic effects).

How long does a topical application weed high last? It doesn’t.

Sublingual Administration

Sublingual is the scientific word for “putting something under your tongue and letting it dissolve.” After a few minutes, that substance — in this case, some type of cannabis product — is absorbed into your bloodstream through the arteries in your jaw, where it travels directly to your brain.

Sublingual consumption of marijuana is one of the easiest, fastest, and most discreet methods available today. Products for sublingual consumption include:

How long does a sublingual administration weed high last? 2-4 hours

A Special Situation (Wink, Wink, Nudge, Nudge)

Woman wondering, how long does weed high last

Yes, we’re talking about sex here (that’s what the winks and nudges were for). Bet you didn’t know there was a cannabis product made especially with that in mind. It’s called cannabis lube, and it’s designed with her in mind (meaning guys don’t use it).

Cannabis lube doesn’t get you high, but it does get things working and relaxed down there (if you catch our drift). That makes for better, more enjoyable intimacy on both sides of the equation.

How long does a special situation weed high last? Technically, you won’t get high at all, but you might feel euphoric in other ways.

Now that you get a general sense of how long a weed high lasts based on the method of consumption you choose, let’s examine some other factors that affect duration.

Other Factors That Affect How Long A Weed High Lasts

1) Quality

Organic marijuana

Quality plays an important role in determining how long a weed high lasts. High-quality, organic marijuana that’s rich in cannabinoids, terpenes, and trichomes will provide a much more satisfying high than the low-quality mids or regs you might be used to.

It’s worth the extra money for the chance to stretch your weed high out just a little bit longer.

2) Strain

The strain you choose can also have an impact on how long your weed high lasts. Stronger strains can make it seem like your high lasts longer because the effects are so much more dramatic.

But before you rush out to buy the strongest weed strain money can buy, keep in mind that with extreme highs come extreme lows and side effects.

Because strong weed strains are bred for high THC and low CBD, there are fewer cannabinoids to counteract the negative effects of THC (e.g., paranoia, anxiety, etc.).

3) THC Content

THC content plays a large role in the quality of experience you can expect from your marijuana product. Breeders are growing whole bud that contains 25-percent THC.

THC extracts are even pushing the coveted triple-digit THC percentage (that’s 100-percent, boys and girls).

With these big-number products, weed highs may seem longer because the “distance” you have to travel from peak high to normal is so much greater.

4) Experience

Your experience dating Mary Jane also plays a big part in how long a weed high lasts. Think of this as your tolerance to the cannabinoids that marijuana has to offer.

As with any drug, your body will eventually get used to processing the THC in your joint, so you’ll need more just to feel the same effects.

That can have a dramatic impact on the duration of your high. If you’re a brand-new cannaseur, you’ll likely trip balls for quite some time after just one or two tokes.

But if you’re a seasoned canna-warrior, you may only feel high for 10 minutes on the strongest weed strain available. That’s the benefit and the curse of experience with the wacky weed.

5) Amount Consumed

Marijuana blunts

The amount of pot you consume has a direct effect on how long a weed high lasts.

Think about it: if you take two drags on a blunt over the course of five minutes, your weed high isn’t going to last anywhere near as long as if you take 20 drags on several blunts over the course of 45 minutes.

Even smoking two blunts (or joints or whatever) in 20 minutes is going to bring on a high that lasts longer than those initial two tokes in five minutes.

6) Your Metabolism

The speed with which your body processes food, drink, medications, and other “foreign” substances (your metabolism) also affects how long a weed high lasts.

If you have a fast metabolism, your body processes outside materials very quickly. That means the THC will spend a shorter time in your brain and blood (which results in a short high).

If you have a slow metabolism, your body processes outside materials slowly. That means the THC will spend longer in your brain and blood (which results in a long high).

7) Environment

Woman ponder the question how long does weed high last

No, we’re not talking about global warming here — it’s not that type of environment. The environment in this case refers to whether or not your surroundings are relaxing and familiar or tense and strange.

If you’re at home in your favorite chair with a classic stoner movie on the tube or playing a fun weed game, your high is going to last quite a long time.

But if you’re hunkered down behind a dumpster in some strange alley on the opposite side of town, your nerves are going to decrease the weed high substantially.

For the best experience, find a relaxing environment where you can chill for a while without worrying about what’s going on around you.

Focus On The Effects, Not The Duration

Man smoking weed

Most marijuana highs will peak after 30 minutes (on average) and then start to trail off. You’ll still feel the effects for another hour or two, but they’ll gradually get less and less intense.

And what’s more, they all pretty much last the same amount of time (give or take an hour or two).

So rather than worrying overly much about how long a weed high lasts, focus instead on the effects you experience. Ask yourself:

  • Was the high too harsh?
  • Was it too weak?
  • Did the weed high make you sad?
  • Did it make you paranoid?
  • How did you feel coming out of it?
  • Were the munchies really intense?

If you can find a strain or potency that gives you all the good without the bad, that’s worth its weight in gold. A totally pleasurable experience that only lasts for two hours is much better than an unpleasant experience that lasts for six.

Focus on the effects, not the duration, and you’ll be a happy canna-camper just like us.

For more information on all things cannabis and to check out our 100-percent all-natural marijuana products, visit HonestMarijuana.com today.

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NY: Medical marijuana program adds acute pain management as qualifying condition

On Monday, September 24, Gov. Andrew Cuomo signed a bill that adds acute pain management to the list of approved conditions eligible for treatment with medical marijuana as an alternative to opioid use. This new law formalizes regulations the New York State Department of Health issued in July, which added opioid replacement and opioid use disorder to the list.

This is great news for patients! Access to medical marijuana is no longer limited to those suffering from chronic pain. This bill and regulations allow more patients who could benefit from medical marijuana a safe and effective alternative to highly addictive opioids.

Find more information on New York’s medical marijuana program, including the list of qualifying conditions and how to register, here.

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Study: Cannabinoids May Inhibit Tumor Growth in Triple Negative Breast Cancer

According to a new study published by the journal Photodiagnosis and Photodynamic Therapy, cannabinoids may inhibit tumor growth in triple negative breast cancer.

The study states that “Triple negative breast cancer (TNBC) is the deadliest form of breast cancer because compared with other types of breast cancer, it is more aggressive, diagnosed at later stage and more likely to develop recurrence”. Many patients “do not experience adequate tumor control after current clinical treatments involving surgical removal, chemotherapy and/or radiotherapy, leading to disease progression and significantly decreased quality of life.”

Here researchers “report a new combinatory therapy strategy involving cannabinoid-based medicine and photodynamic therapy (PDT) for the treatment of TNBC.” They found that “the combined CB2R agonist and TSPO-PDT treatment resulted in synergistic inhibition in TNBC cell and tumor growth.”

The study concludes; “This combinatory therapy approach provides new opportunities to treat TNBC with high efficacy. In addition, this study provides new evidence on the therapeutic potential of CB2R agonists for cancer.”

For the full study, click here.

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New York Governor Signs Bill Adding Pain Management to List of Medical Cannabis Conditions

Governor Andrew Cuomo yesterday signed legislation (S8987A/A 11011-B) that adds acute pain management to the list of conditions for which medical marijuana can be recommended as an alternative to opioid use.

The bill will also allow for substance use disorder treatment providers to recommend medical marijuana to help patients manage underlying pain that contributes to the abuse of substances such as opioids.

“In this battle against the opioid epidemic, it is critical that we use every means at our disposal to prevent the unnecessary prescription of these dangerous and addictive painkillers,” Governor Cuomo said. “Adding these conditions to the list of those approved for management with medical marijuana will help reduce the risk of addiction and provide suffering New Yorkers the relief they need.”

“We know that medical marijuana can be a helpful alternative for a wide range of illnesses and conditions,” said Lieutenant Governor Kathy Hochul. “By expanding the approved list, we are providing New Yorkers with new options, and preventing the danger that comes from opioid addiction.”

The bill will formalize into law the regulatory change that was implemented by the Department of Health earlier this year that added opioid replacement and opioid use disorder to the existing list of conditions for which a patient can qualify for medical marijuana. In order to recommend medical marijuana for pain management, a registered practitioner must determine that the patient’s pain degrades health and functional capability, along with certain other requirements.

Senator George Amedore, Chairman of the Senate Standing Committee on Alcoholism and Substance Abuse said, “As the Senate Task Force on Heroin and Opioid Addiction travelled the state, this was a big gap that we heard about over and over. When we look at solutions to help us combat the heroin and opioid epidemic, we must ensure prescribers and patients have every resource and option at their disposal. I’m glad the Governor has signed this legislation that will help patients and provide an alternative to highly addictive opioids.”

Assembly Health Committee Chair and bill sponsor Richard N. Gottfried said, “Opioid addiction does not discriminate, impacting New Yorkers of all ages, genders, and races. Evidence from across the country shows that access to medical marijuana for pain treatment reduces the use of far more dangerous opioids. Medical marijuana is a safe and effective alternative for treating pain.  I commend the Governor for signing the bill and will continue working to expand access to medical marijuana for patients in need.”

Assembly Member Linda B. Rosenthal, Chair of the Assembly Committee on Alcoholism and Drug Abuse said, “People seeking treatment for substance use disorder and those afflicted with chronic pain must have access to the best array of medical options. By adding substance use disorder and pain management to the list of conditions eligible for treatment with medical marijuana, we will be allowing New Yorkers to take advantage of a harm reduction technique that can be used as an alternative to highly addictive opioids. I thank Governor Cuomo for signing this provision into law and providing us with yet another tool to combat the public health crisis of opioid addiction and overdose.”

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Tuesday 25 September 2018

Mormons Oppose Marijuana Initiative in Utah Despite History of Cannabis Use

Mormons with Mexicans in Northern Mexico, 1908

In 1885, the prophet and president of the Mormon Church, John Taylor, purchased about 100,000 acres of land in Mexico—in Chihuahua and Sonora, to be exact, some 200 miles south of the US border. More than 300 polygamous Mormon families from Utah migrated south to settle the land and to proselytize (even today you see the traveling twosomes of fresh-faced young men in their white shirts, ties and black name tags) and, many theorize, to preserve the practice of polygamy.

At the time, Mormon polygamists were being jailed and having their property seized. Utah itself was denied statehood by the federal government to halt the practice. Former presidential candidate Mitt Romney is descended from the Mexican settlements; his father, George, and grandfather, Marion, were born in Colonia Dublán, Mexico, in 1907.

But in 1910, many who had settled in northern Mexico began an exodus back to Utah due to anti-American sentiment fueled by the Mexican Revolution. Some say they returned with a local plant introduced by the natives: cannabis.

The Mormon Church, formally known as the Church of Jesus Christ of Latter-Day Saints (LDS), were and still are infamous for their teetotaler ways and as abstainers of vices of all kinds; hence, they didn’t look kindly on the brethren partaking of the plant, viewing it as a violation of Mormon scripture from the “Doctrine and Covenants,” section 89 (D&C 89), commonly referred to as the “Word of Wisdom.”

Mormon Church founder Joseph Smith

Church founder and prophet Joseph Smith wrote D&C 89 at the strong urging of his wife, Emma, who was tired of Smith’s friends gathering in their home and spitting tobacco on the floor. But Smith went far beyond forbidding tobacco; D&C 89 also bans the use of wine, coffee, tea and liquor. And it promises that those who follow the doctrine will receive health, protection, knowledge and wisdom from God.

So when the settlers returned from Mexico with marijuana in hand, church leadership urged the legislature to officially outlaw cannabis in 1915. Four years earlier, Massachusetts became the first state to prohibit marijuana, followed by California, Indiana, Maine and Wyoming in 1913; New York in 1914; Utah and Vermont in 2015; and Colorado and Nevada in 1917.

19th Century map of Mormon colonies in Mexico

This version of events seems to have first appeared in 1995, when a University of Southern California law professor, Charles Whitebread, floated his theory in a speech to the California Judges Association, “The History of Non-Medical Use of Drugs in the United States.” Riddled with historical and cultural inaccuracies, Whitebread said that he “had help from some people in Salt Lake City associated with the Mormon Church and the Mormon National Tabernacle in Washington,” which does not exist.

At the instruction of Smith’s successor, Brigham Young, 19th-century Mormons became incredibly self-sufficient, raising their own cotton, flax, silk and, yes, hemp to limit interactions with non-Mormons. In the Journal of Discourses, a pioneer-era magazine written by church leadership in the late-1800s, leaders advised members, “We must make our own woolen, flax, hemp and cotton goods or we must go naked.”

Nonetheless, Whitebread drew the line straight from Mexico to Salt Lake City and blamed the cannabis ban on the morals of the church. Mormon historian Ardis E. Parshall challenges Whitebread’s logic in her 2009 article, “The Great Mormon Marijuana Myth,” a comprehensive, if dense, takedown citing LDS conference talks, newspaper editorials and even arrest records, making Whitebread’s explanation much less tidy.

Former presidential candidate Mitt Romney is descended from the Mexican settlements; his father, George, and grandfather, Marion, were born in Colonia Dublán, Mexico, in 1907.

“There is no hint whatsoever that Utah’s law—which you now see did not specifically target marijuana or even show particular awareness of marijuana, but merely incorporated the language used by other entities to name marijuana among a whole host of regulated drugs—was spurred by religious concerns,” Parshall wrote.

Parshall’s contention that religion had nothing to do with the original 1915 ban, however, does not seem to hold much water today. In November, Utahans will have the opportunity to vote on Prop 2, a.k.a. the Utah Medical Cannabis Act—a ballot initiative that, if it passes, will blow open Utah’s legal cannabis landscape.

LDS leadership has taken a position against Prop 2, even going so far as to commission Salt Lake City law firm Kirton McConkie to conduct a legal analysis of its implications. In May, based on the firm’s findings, the church concluded that “serious adverse consequences could follow if it were adopted,” citing “grave concerns,” like an increase in youth use, a lack of traditional research, taking power out of the hands of pharmacists, a mandate to destroy patient records after 60 days and providing legal cover to doctors that make recommendations.

DJ Schanz speaks at a Utah Patients Coalition event.

Even though Prop 2 has strong support among Utah voters, the Utah Patients Coalition (UPC), the group spearheading the legalization effort, has faced stiff opposition—and some would argue shady tactics—from Drug Safe Utah, the anti-legalization group that tried to keep medical marijuana off the ballot.

Comprised of the Utah Medical Association, the ultra-Conservative Eagle Forum, the Sutherland Institute and the Utah Chiefs of Police Association, Drug Safe is closely aligned with the all-male church leadership. Drug Safe has received $167,000 contributions (including $100,000 from a private citizen named Walter J. Plumb III and $20,000 from the Medical Association). UPC has raised $767,000 (including $261,000 from the Marijuana Policy Project and $50,000 from Dr. Bronner’s).

The Mormon church has not been shy about stating their views, especially around matters that intersect with perceived moral issues like drug use. For example, leadership counseled its members in 2008 to vote for California’s Prop 8 initiative that made gay marriage illegal and applied the same tactic with recreational cannabis initiatives in Nevada and California. When given as a directive, members tend to rally behind church guidance.

UTAH PATIENTS COALITION’S DJ SCHANZ: “The challenge in Utah, which may be somewhat unique to our state, is the influence that a single religious denomination can have on a huge swath of the population.”

Mormons are not necessarily opposed to cannabis, per se, but have strong opinions about how and why it should be used. Opinions about Prop 2 seems to boil down to the word “medical.” A Dan Jones & Associates poll from 2016 showed that support even then for medical marijuana hovered around 66%. But when asked about legalizing recreational marijuana, the results were flipped, with 77% opposed.

“The challenge in Utah, which may be somewhat unique to our state, is the influence that a single religious denomination can have on a huge swath of the population,” UPC’s campaign director DJ Schanz tells Freedom Leaf. “It’s a constant balancing act of winning over supporters in this demographic without being confrontational and abrasive to the organization, even with said religious organization’s subtle efforts to derail the ballot initiative.”

Currently, Utah has a very restrictive, lawmaker-driven medical marijuana program in place. HB 195 allows those diagnosed with terminal illnesses access to medicinal cannabis and HB 105 (a.k.a. Charlee’s Law, named for Charlee Nelson, was enacted in 2014) permits CBD-only treatment for children with intractable epilepsy.

Utah Patients Coalition

Many stakeholders and policymakers in Utah believe marijuana can’t be a medicine if it’s smoked. Prop 2 does not allow for marijuana to be packages pre-rolls and specifies vaping only. Section 51 reads, in part:

“(6)(a) Except as provided in Subsection (6)(b), a cannabis dispensary may not sell medical cannabis in the form of a cigarette or a medical cannabis device that is intentionally designed or constructed to resemble a cigarette.

“(b) A cannabis dispensary may sell a medical cannabis device that warms cannabis material into a vapor without the use of a flame and that delivers cannabis to an individual’s respiratory system.”

H.B. 195 is also smoke-free.

Mormons are not necessarily opposed to cannabis, per se, but have strong opinions about how and why it should be used.

In the view of church leadership and many members, marijuana used in any way outside of a strictly-regulated, medicinal application turns it into a habit-forming and addictive narcotic. This leaves faithful members and ward leaders feeling torn about medical use, especially since the church has not provided clear guidance.

At a 2010 conference in Colorado Springs, priesthood leaders were asked what the official church policy was on medical cannabis. “It’s an issue between the church member, the member’s bishop and the Lord, to be made in consultation with the scriptures and Word of Wisdom,” was the general answer, the Salt Lake Tribune reported.

A Mormon bishop who wishes not to be named says he hasn’t had any members ask him for advice about using medical marijuana yet, but is certain it will eventually come up. “The counsel I would give them would have a lot to do with specific circumstances,” he confides. “I hope this is an evolving policy and that [church leaders] are open to further clarification in the future.”

Temple Square in Salt Lake City, UT

The church says they want more research, stating: “It’s in the public’s best interest, when new drugs undergo the scrutiny of medical scientists and official approval bodies.” Even Mormon Senator Orrin Hatch (R-UT) is pressing the federal government to lift the delays on cannabis research approvals.

But none of this may matter to Utah voters, about half of whom are active Mormons. A late August Dan Jones & Associates poll indicated that, despite the church’s vigorous disapproval, support for the initiative remains high, at about 64%, though down from 78% in July.

Unless the winds shift, Prop 2 will most likely pass. Win or loss, when Utahans wake up on Nov. 7, they’ll still be tussling with the church about marijuana. Guaranteed.

More Marijuana Ballot Initiatives in 2018

Michigan Is Poised to Become the 10th State to Legalize It

Dueling Initiatives in Missouri Likely to Confuse Voters

Recreational Legalization on the North Dakota Ballot

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